Radioactivity studies on 2 synovial specimens after radiation synovectomy with yttrium-90 silicate.

Radiation synovectomy with yttrium--90 silicate.

Yttrium-90 radiation synovectomy in knee osteoarthritis: a prospective assessment at 6 and 12 months.

OBJECTIVE To assess the outcome of yttrium-90 radiation synovectomy at 6 and 12 months in patients with knee osteoarthritis unresponsive to systematic or local medical treatment. METHODS Consecutive patients with osteoarthritic knee pain resistant to conventional therapy and submitted to intraarticular yttrium-90 treatment because of synovial inflammation, as demonstrated by early-phase bone ...

Histological study of effects of colloidal 90 yttrium on knee joint tissues of rabbits.

The administration of 0-2-0-4 mCi 90 yttrium (90Y) into a normal rabbit knee joint fails to induce medical synovectomy and results in the proliferation of the synovialis. The synovial mesothelium shows early radiation damage but subsequently follows a restitution of the whole. Later (within 4 to 16 weeks) an extensive fibrosis of the stratum synovialis develops, as well as an occlusion and scle...

Long term follow up of radiosynovectomy with yttrium-90 silicate in haemophilic haemarthrosis.

OBJECTIVES The aim of this study was to evaluate the long term effect of radiation synovectomy with yttrium-90 silicate in haemophiliac patients with recurrent haemarthrosis. METHODS The bleeding frequency and the mobility of the joint were recorded in 16 joints of 14 patients 1 year before radiosynovectomy and during follow up, which ranged from 3 to 6 years. Patients evaluated the effect of...

Radioactive yttrium in the treatment of rheumatoid knee effusions. Preliminary evaluation.

Irradiation of the synovium for the treatment of chronic knee effusions associated with rheumatoid arthritis and allied conditions is being increasingly used as an alternative to surgical synovectomy. Intraarticular injections of a colloidal solution of radioactive gold (19"8Au) has been tried with some success (Ansell, Crook, Mallard, and Bywaters, 1963; Virkkunen, Krusius, and Heiskanen, 1967...